What?? I'm going to believe you made a mistake typing that; the way I read that says if you can't hit your target with a .45, you just suck and can't hit it with anything... if I'm misunderstanding that, please clarify.
Harold is a really, really good guy, tough as nails. His daughter Jennifer used to babysit my kids. I remember the day we were talking about the shooting; he opened his shirt, and man. What a mass of scars on his torso. He counted each one for me. Then he smiled that big, toothy grin of his, and told me all he had behind the counter was a ball bat. He told me, "I'm here. He ain't."
Service calibers have a much better probability of doing the job; that's why they're service calibers. ANY caliber is capable of doing the job, however.